BDBM50633108 CHEMBL5430918

SMILES O\N=C(\NCCc1ccc(Cl)cc1)c1nonc1NCCCc1nnc(NC(=O)Cc2ccc(O)cc2)s1

InChI Key InChIKey=IBPCGLXMRQYGNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633108   

TargetThioredoxin reductase 1, cytoplasmic(Rat)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633108(CHEMBL5430918)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of recombinant rat TrxR1 incubated for 1 hr in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Wannan Medical College

Curated by ChEMBL
LigandPNGBDBM50633108(CHEMBL5430918)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human IDO1 using L-Trp as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed