BDBM50633011 CHEMBL5409419::US20250109139, Compound I-A2

SMILES COc1cccc2c3CCN(CCCCOc4ccc5CCC(=O)Nc5c4)Cc3oc12

InChI Key InChIKey=UCGXXGOWEGSYJJ-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50633011   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]-LSD from 5-HT1A receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D3 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D4 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-SCH23390 from Dopamine D1 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D2 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  113nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetD(1B) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  159nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D5 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  611nMAssay Description:Displacement of [3H]-LSD from 5-HT2C receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]-LSD from 5-HT2A receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  1.11E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent