BDBM50633010 CHEMBL5426242::US20250109139, Compound I-A1

SMILES COc1cccc2c3CCN(CCCCOc4ccc5ccc(=O)[nH]c5c4)Cc3oc12

InChI Key InChIKey=ULYBTXJNQXAQFS-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50633010   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-LSD from 5-HT1A receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D3 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D4 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D2 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  84.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  189nMAssay Description:Displacement of [3H]-SCH23390 from Dopamine D1 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  555nMAssay Description:Displacement of [3H]-LSD from 5-HT2C receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D5 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  1.79E+3nMAssay Description:Displacement of [3H]-LSD from 5-HT2A receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  1.79E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent