BDBM50632814 CHEMBL5417686

SMILES COc1cc(Cn2c(cc3cc(ccc23)-c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)C(=O)N2CCc3cc(OC)c(OC)cc3C2)cc(OC)c1

InChI Key InChIKey=KZCXKPNIJGNSPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50632814   

TargetATP-dependent translocase ABCB1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50632814(CHEMBL5417686)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of P-gp-mediated multidrug resistance in doxorubicin-resistant human MCF7/ADR cells assessed as potentiation of doxorubicin-induced cytoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed