BDBM50632782 CHEMBL5394148

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)c1cc2cc(ccc2[nH]1)-c1ccc(NC(=O)c2cccc(Cl)c2)cc1

InChI Key InChIKey=GJSWHZMXYKPVOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50632782   

TargetATP-dependent translocase ABCB1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50632782(CHEMBL5394148)
Affinity DataIC50: 114nMAssay Description:Inhibition of P-gp-mediated multidrug resistance in doxorubicin-resistant human MCF7/ADR cells assessed as potentiation of doxorubicin-induced cytoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed