BDBM50632674 CHEMBL5407071

SMILES C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CCN(C)CC1

InChI Key InChIKey=PDAOEKSLYKFTKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632674   

TargetC-C chemokine receptor type 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50632674(CHEMBL5407071)
Affinity DataIC50: 24nMAssay Description:Antagonist activity against CCR8 (unknown origin) expressed in CHO-K1 cells preincubated for 1 hr followed by CCL1 addition measured after 24 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetC-C chemokine receptor type 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50632674(CHEMBL5407071)
Affinity DataIC50: 34nMAssay Description:Inhibition of CCR8-mediated cell migration in CCL1-induced human PBMC preincubated for 1 hr followed by CCL1 addition measured after 4 hrs by cell co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed