BDBM50632650 CHEMBL5421905

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=BPNIVDNFCGVIJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632650   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50632650(CHEMBL5421905)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-treated human THP-1 cells assessed as inhibition of ATP-stimulated IL-1beta release at 1 uM incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50632650(CHEMBL5421905)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-treated mouse BMDM cells assessed as inhibition of ATP-stimulated IL-1beta release incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed