BDBM50632348 CHEMBL5400371

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)CCCCc3cc3=O)c2)n1)N1CCN(CC1)C(=O)CCC#C

InChI Key InChIKey=GJXOPGLSLPNZSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632348   

TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50632348(CHEMBL5400371)
Affinity DataIC50: 210nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) using Tyr 04 peptide as substrate incubated for 1 hrs in the presence of ATP by FRET-based Z'-Lyte a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlutathione S-transferase P(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50632348(CHEMBL5400371)
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant GSTP1 (unknown origin) using GSH as substrate incubated for 5 mins by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed