BDBM50632259 CHEMBL5395577

SMILES CCCOC(=O)c1sc(NC(=O)C[C@H](CCCNC(=O)CCCCC[N+]2=C(\C=C\C=C\C=C3\N(C)c4ccc(cc4C3(C)C)S(O)(=O)=O)C(C)(C)c3cc(ccc23)S(O)(=O)=O)NC(=O)c2cccc(c2)-c2noc(C)n2)nc1C

InChI Key InChIKey=OKRADMZDWCYHHR-UHFFFAOYSA-O

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50632259   

TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50632259(CHEMBL5395577)
Affinity DataKd:  315nMAssay Description:Binding affinity to N-terminal His-tagged full length recombinant human HSET assessed as dissociation constant incubated for 3 hrs in presence of 7 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50632259(CHEMBL5395577)
Affinity DataIC50: 257nMAssay Description:Inhibition of N-terminal His-tagged full length recombinant human HSET assessed as inhibition of microtubule-stimulated ATPase activity incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50632259(CHEMBL5395577)
Affinity DataKd:  371nMAssay Description:Binding affinity to N-terminal His-tagged full length recombinant human HSET assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50632259(CHEMBL5395577)
Affinity DataKd:  332nMAssay Description:Binding affinity to N-terminal His-tagged full length recombinant human HSET assessed as dissociation constant incubated for 3 hrs in presence of 70 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed