BDBM50632183 CHEMBL5395896

SMILES CN(C)C(=O)CCN(C(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)c1cc2cc(ccc2s1)C(F)(F)P(O)(O)=O)c1ccc(cc1)-c1nccs1

InChI Key InChIKey=FXSGEOMFUMJYFF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50632183   

TargetSignal transducer and activator of transcription 5A(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632183(CHEMBL5395896)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to N-terminal 6his-tagged human STAT5A (136 to 705 residues) expressed in Escherichia coli BL21-DE3 rosetta cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632183(CHEMBL5395896)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to STAT5B (unknown origin) assessed as inhibition constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632183(CHEMBL5395896)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity to STAT6 SH2 domain (unknown origin) assessed as inhibition constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed