BDBM50632179 CHEMBL5396273

SMILES CC(C)(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N(CCC(=O)N(C)C)c2ccc3c(c2)cco3)NC(=O)c4cc5cc(ccc5s4)C(F)(F)P(=O)(O)O

InChI Key InChIKey=UTADYHXHDMKUES-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50632179   

TargetSignal transducer and activator of transcription 6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632179(CHEMBL5396273)
Affinity DataKi:  200nMAssay Description:Binding affinity to STAT6 SH2 domain (unknown origin) assessed as inhibition constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632179(CHEMBL5396273)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to STAT5B (unknown origin) assessed as inhibition constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSignal transducer and activator of transcription 5A(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632179(CHEMBL5396273)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity to N-terminal 6his-tagged human STAT5A (136 to 705 residues) expressed in Escherichia coli BL21-DE3 rosetta cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)