BDBM50632076 CHEMBL5405439

SMILES Oc1c(F)ccc(-c2ncc(Cn3ccc(=O)n(CC(F)(F)F)c3=O)s2)c1F

InChI Key InChIKey=INXBNOVRZZLIIX-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50632076   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632076(CHEMBL5405439)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632076(CHEMBL5405439)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 expressed in HEK293 cells using estradiol as substrate preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632076(CHEMBL5405439)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant mouse full-length C-terminal His-tagged HSD17B13 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632076(CHEMBL5405439)
Affinity DataKi:  4nMAssay Description:Tight binding inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 assessed as inhibition constant by morrison equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed