BDBM50632044 CHEMBL5417785

SMILES Cn1cnc2n(CC#Cc3cccc(O)c3)c(=O)n(C)c(=O)c12

InChI Key InChIKey=VZMYBKUBNJJYQD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50632044   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B11 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 expressed in HEK293 cells using estradiol as substrate preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant mouse full-length C-terminal His-tagged HSD17B13 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50632044(CHEMBL5417785)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B13 using retinol as substrate and NAD as cosubstrate preincubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed