BDBM50631854 CHEMBL5410484

SMILES CN1CC(C1)C(=O)NCc1ccc2c(cn(C3CCC(CC3)S(=O)(=O)C(F)(F)F)c2c1)-c1cccc(c1)C(N)=S

InChI Key InChIKey=KTQRJENQPCCJPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50631854   

TargetHistone-lysine N-methyltransferase ASH1L(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50631854(CHEMBL5410484)
Affinity DataIC50: 790nMAssay Description:Inhibition of N-terminal Mocr-tagged ASH1L (2069 to 2288 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed