BDBM50631721 CHEMBL5418423

SMILES NC(=O)CCn1cc(nn1)-c1ccc2ncnc(Nc3cc(O)c(F)cc3F)c2c1

InChI Key InChIKey=MKVJEWXMOVKCHS-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50631721   

LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant VEGFR-2 in the presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631721(CHEMBL5418423)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 73nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 57nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 57nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50631721(CHEMBL5418423)
Affinity DataIC50: 73nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50631721(CHEMBL5418423)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed