BDBM50631686 CHEMBL5395937

SMILES COc1nc(O[C@H]2CCc3c2cccc3-c2cccc(C(=O)Nc3ccc(CNC[C@@H]4CCC(=O)N4)cn3)c2Cl)c(Cl)cc1CNC[C@@H]1CCC(=O)N1

InChI Key InChIKey=OAIVRAFLXRHGNX-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50631686   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631686(CHEMBL5395937)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of interaction of Fc(IgG1)-Avi)-(Biotin)-fused human PDL1 (19 to 239 residues)/Eu-labeled human PD-1 (25 to 167 residues) expressed in HEK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631686(CHEMBL5395937)
Affinity DataKd:  24nMAssay Description:Binding affinity to RED-NHS dye labeled human PDL1 incubated for 10 mins away from light by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631686(CHEMBL5395937)
Affinity DataKd:  790nMAssay Description:Binding affinity to RED-NHS dye labeled mouse PDL1 incubated for 10 mins away from light by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed