BDBM50631146 CHEMBL5427975

SMILES Cc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NC2CCC(=O)NC2=O)cc1Cl

InChI Key InChIKey=UPQKJUKBBWRZJU-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631146   

TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL

LigandBDBM50631146(CHEMBL5427975)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/21/2024
Entry Details
Copy Entry DOIPubMed
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TargetEukaryotic peptide chain release factor GTP-binding subunit ERF3A(Human)
Bristol Myers Squibb

Curated by ChEMBL

LigandBDBM50631146(CHEMBL5427975)Copy SMILESCopy InChI

Affinity DataEC50:  100nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL