BDBM50631143 CHEMBL5430384

SMILES O=C1CCC(C(=O)N1)n1cnc2ccc(OCc3ccc(CN4CCOCC4)cc3)cc12

InChI Key InChIKey=STPAWIJDTOCXOB-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631143   

TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL

LigandBDBM50631143(CHEMBL5430384)Copy SMILESCopy InChI

Affinity DataEC50:  70nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/21/2024
Entry Details
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TargetEukaryotic peptide chain release factor GTP-binding subunit ERF3A(Human)
Bristol Myers Squibb

Curated by ChEMBL

LigandBDBM50631143(CHEMBL5430384)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL