BDBM50631128 CHEMBL5424221::US20250127903, Compound 187

SMILES O=C1CCC(C(=O)N1)n1ncc2ccccc12

InChI Key InChIKey=MXJZNPWGQKNANB-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631128   

TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631128(CHEMBL5424221 | US20250127903, Compound 187)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM50631128(CHEMBL5424221 | US20250127903, Compound 187)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent