BDBM50631110 CHEMBL5435641

SMILES C[C@@H]1CCCN1c1cc2C(=O)N(Cc2c(n1)[C@H](N)CN)c1cccc(n1)-c1nnc2CC[C@H](C)n12

InChI Key InChIKey=AUOFLQBOFKWOGI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631110   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50631110(CHEMBL5435641)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition of SLP-76 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50631110(CHEMBL5435641)
Affinity DataKi: <0.0500nMAssay Description:Inhibition of HPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed