BDBM50631004 CHEMBL5430391

SMILES CCn1ncc2c(NC(P(O)(O)=O)P(O)(O)=O)nc(nc12)-c1cccc(c1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XMLGVHAUDPAVAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50631004   

TargetGeranylgeranyl pyrophosphate synthase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50631004(CHEMBL5430391)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His6 tagged human GGPPS expressed in Escherichia coli BL21(DE3) cells in presence of FPP and [14C]IPP by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed