BDBM50630953 CHEMBL5436104

SMILES [H][C@]12C[C@]3([H])C[C@]([H])(C1)CC(CNC(=O)c1ccc4n(Cc5ccc(C(=O)NO)c(F)c5)ccc4c1)(C2)C3

InChI Key

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50630953   

TargetHistone deacetylase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant full-length human HDAC1 using FITC-H3K27(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant full-length human HDAC2 using FITC-H3K27(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant full-length human HDAC3 using FAM-RHKK(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant full-length human HDAC4 using FAM-RHKK (trifluor-Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant full-length human HDAC5 using FAM-RHKK (trifluor-Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full-length human HDAC6 using FAM-RHKK(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant full-length human HDAC7 using FAM-RHKK (trifluor-Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant full-length human HDAC8 using FAM-RHKK(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant full-length human HDAC9 using FAM-RHKK (trifluor-Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant full-length human HDAC10 using FITC-H3K27(Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50630953(CHEMBL5436104)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant full-length human HDAC11 using FAM-RHKK (trifluor-Ac)-NH2 as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed