BDBM50630592 CHEMBL5424655

SMILES Nc1ccc(cc1)C(=O)NC1CCC(=O)NC1=O

InChI Key InChIKey=JBOKBLSWHXNCMS-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50630592   

TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50630592(CHEMBL5424655)
Affinity DataIC50: 8.60E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50630592(CHEMBL5424655)
Affinity DataEC50:  607nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50630592(CHEMBL5424655)
Affinity DataKi:  4.10E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed