BDBM50630536 CHEMBL5431378

SMILES CCS(=O)(=O)Nc1nc(c(s1)-c1ccnc(Nc2cc(C)c(cc2OC)N2CCC(CC2)N2CCN(C)CC2)n1)-c1ccc(F)cc1

InChI Key InChIKey=JXCBRDPJRKVYGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50630536   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50630536(CHEMBL5431378)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using polyE4Y1 as substrate incubated for 5 mins with compound followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed