BDBM50630531 CHEMBL5416812

SMILES CCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2sc(NS(=O)(=O)CC)nc2-c2ccc(F)cc2)cc1

InChI Key InChIKey=GUVUQZFKKFVDHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50630531   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50630531(CHEMBL5416812)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using polyE4Y1 as substrate incubated for 5 mins with compound followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed