BDBM50630525 CHEMBL5432141

SMILES CCCCS(=O)(=O)Nc1nc(c(s1)-c1ccnc(Nc2ccc3n(CCN(C)C)ccc3c2)n1)-c1ccc(F)cc1

InChI Key InChIKey=VBMFDVSLSLWWJV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50630525   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50630525(CHEMBL5432141)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using polyE4Y1 as substrate incubated for 5 mins with compound followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed