BDBM50630491 CHEMBL5423228

SMILES CC(C)OC(=O)[C@@H](Cn1cncn1)OC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=JEXSOFPQDXJKCO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630491   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50630491(CHEMBL5423228)Copy SMILESCopy InChI

Affinity DataIC50: 0.580nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
Copy Entry DOIPubMed
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TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50630491(CHEMBL5423228)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of NLRP3 inflammasome activation in human whole blood assessed as inhibition of LPS/ATP induced IL-1beta secretion preincubated with LPS f...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL