BDBM50630488 CHEMBL5438164

SMILES CCOC(=O)C(Cn1cc(cn1)C#N)OC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=BNTFPXZQMMYARR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630488   

LigandPNGBDBM50630488(CHEMBL5438164)
Affinity DataIC50: 2nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandPNGBDBM50630488(CHEMBL5438164)
Affinity DataIC50: 13nMAssay Description:Inhibition of NLRP3 inflammasome activation in human whole blood assessed as inhibition of LPS/ATP induced IL-1beta secretion preincubated with LPS f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed