BDBM50630482 CHEMBL5406685

SMILES CCOC(=O)COC(=O)Nc1c(F)cccc1F

InChI Key InChIKey=VCDVKFGTAIUQEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630482   

LigandPNGBDBM50630482(CHEMBL5406685)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandPNGBDBM50630482(CHEMBL5406685)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in human whole blood assessed as inhibition of LPS/ATP induced IL-1beta secretion preincubated with LPS f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed