BDBM50630435 CHEMBL5407732

SMILES C[C@]1(COC[C@@H]1O)N2CCC(CC2)c3cc4cc(ncc4cc3Cl)NC(=O)C5CC5

InChI Key InChIKey=AUWBKRNKWPJDOB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630435   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50630435(CHEMBL5407732)Copy SMILESCopy InChI

Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) using LRRKtide peptide as substrate assess...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
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TargetSerine/threonine-protein kinase BRSK1(Human)
Merck

Curated by ChEMBL

LigandBDBM50630435(CHEMBL5407732)Copy SMILESCopy InChI

Affinity DataIC50: 43nMAssay Description:Inhibition of BRSK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL