BDBM50630431 CHEMBL5410079

SMILES CC(C)c1cn(C[C@H](NC(=O)CNC(=O)CC[C@H](NS(=O)(=O)c2ccc(Cl)c(c2)C(F)(F)F)C(O)=O)C(=O)N[C@H](C(=O)N2CCC[C@H]2CC(N)=O)C(C)(C)C)nn1

InChI Key InChIKey=IGBJKQSUGOMLRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630431   

TargetMatrilysin(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50630431(CHEMBL5410079)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human MMP7 using MOCAc-Pro-Leu-Gly-Leu-A2pr-(Dnp)-Ala-Arg-NH2 as substrate preincubated with compound for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50630431(CHEMBL5410079)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human MMP14 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substrate preincubated with compound for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed