BDBM50630414 CHEMBL5395300

SMILES CC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)CC[C@H](NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F)C(O)=O)c1ccccc1)C(=O)N1CCC[C@H]1CC(N)=O

InChI Key InChIKey=OEOCOYGMMCQQSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630414   

TargetMatrilysin(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50630414(CHEMBL5395300)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human MMP7 using MOCAc-Pro-Leu-Gly-Leu-A2pr-(Dnp)-Ala-Arg-NH2 as substrate preincubated with compound for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50630414(CHEMBL5395300)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant human MMP14 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substrate preincubated with compound for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed