BDBM50630153 CHEMBL5429808

SMILES FC(F)c1nnc(o1)-c1ccc(Cn2nnc(n2)-c2ccccn2)nc1

InChI Key InChIKey=ZTVLPDLCENUSAG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50630153   

TargetHistone deacetylase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC1 incubated for 15 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC2 incubated for 15 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC3 incubated for 10 mins by Spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 60 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC4 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC5 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC7 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC9 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC10 incubated for 45 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC11 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630153(CHEMBL5429808)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed