BDBM50630125 CHEMBL5426703

SMILES CCCNNC(=O)c1ccc(Nc2nc(Nc3ccc(OCCN4CCCC4)cc3)ncc2C)cc1

InChI Key InChIKey=BYQLOPDFWVASHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50630125   

TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50630125(CHEMBL5426703)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-AMC as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50630125(CHEMBL5426703)
Affinity DataIC50: 16nMAssay Description:Inhibition of JAK1 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50630125(CHEMBL5426703)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant BRD4 BD1 (unknown origin) using H4KAc as substrate incubated for 30 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed