BDBM50630117 CHEMBL5424524

SMILES Cc1cnc(Nc2ccc(cc2)C(=O)Nc2ccccc2N)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C

InChI Key InChIKey=FMEUTJXSLMQEMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50630117   

TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50630117(CHEMBL5424524)
Affinity DataIC50: 270nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-AMC as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50630117(CHEMBL5424524)
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK1 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50630117(CHEMBL5424524)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant BRD4 BD1 (unknown origin) using H4KAc as substrate incubated for 30 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed