BDBM50629970 CHEMBL5395771

SMILES Cc1cc(cn(C)c1=O)-c1cc2OCCn3c2c(c1)n(Cc1ccccc1)c3=O

InChI Key InChIKey=QTVSDAUHDJBCAA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50629970   

TargetBromodomain-containing protein 4(Human)
Maruho Co.

Curated by ChEMBL
LigandPNGBDBM50629970(CHEMBL5395771)
Affinity DataIC50: 15nMAssay Description:Displacement of Biotin-tagged [Lys(5,8,12,16)Ac]H4(1 to 21) peptide from GST-tagged BRD4-BD1 (unknown origin) incubated for 3 hrs by HTRF based TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Maruho Co.

Curated by ChEMBL
LigandPNGBDBM50629970(CHEMBL5395771)
Affinity DataIC50: 55nMAssay Description:Displacement of Biotin-tagged [Lys(5,8,12,16)Ac]H4(1 to 21) peptide from BRD4-BD2 (unknown origin) incubated for 3 hrs by HTRF based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Maruho Co.

Curated by ChEMBL
LigandPNGBDBM50629970(CHEMBL5395771)
Affinity DataIC50: 19nMAssay Description:Displacement of Biotin-tagged [Lys(5,8,12,16)Ac]H4(1 to 21) peptide from GST-tagged BRD2-BD1 (unknown origin) incubated for 3 hrs by HTRF based TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Maruho Co.

Curated by ChEMBL
LigandPNGBDBM50629970(CHEMBL5395771)
Affinity DataIC50: 25nMAssay Description:Displacement of Biotin-tagged [Lys(5,8,12,16)Ac]H4(1 to 21) peptide from GST-tagged BRD3-BD1 (unknown origin) incubated for 3 hrs by HTRF based TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
Maruho Co.

Curated by ChEMBL
LigandPNGBDBM50629970(CHEMBL5395771)
Affinity DataIC50: 68nMAssay Description:Displacement of Biotin-tagged [Lys(5,8,12,16)Ac]H4(1 to 21) peptide from GST-tagged BRDT-BD1 (unknown origin) incubated for 3 hrs by HTRF based TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Maruho Co.

Curated by ChEMBL
LigandPNGBDBM50629970(CHEMBL5395771)
Affinity DataIC50: 81nMAssay Description:Inhibition of NanoLuc-tagged full length BRD4 (unknown origin) transfected in HEK293 cells coexpressing histone H4-halo-tagged fusion vector preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed