BDBM50629874 CHEMBL5435681

SMILES CC(C)[C@H]1COC(=O)N1c1nc(N[C@@H](C)c2ccc(cc2)-c2ccc(N(C)C)c(NC(=O)C=C)c2)ncc1F

InChI Key InChIKey=UNWYJXHJZJFHBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629874   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50629874(CHEMBL5435681)
Affinity DataIC50: 630nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as NADPH consumption using alpha-KG as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed