BDBM50629872 CHEMBL5422753

SMILES CCC(=O)NC1CCCN(C1)c1ccc(cc1)[C@H](C)Nc1ncc(F)c(n1)N1[C@H](COC1=O)C(C)C

InChI Key InChIKey=VANJMDOVXJACED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629872   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50629872(CHEMBL5422753)
Affinity DataIC50: 670nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as NADPH consumption using alpha-KG as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed