BDBM50629808 CHEMBL5438272

SMILES CCNc1nc(Nc2cc(F)c(cc2OC)C(=O)NCCCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)ncc1C(F)(F)F

InChI Key InChIKey=NHYGUXAZZSSUPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629808   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629808(CHEMBL5438272)
Affinity DataIC50: 15nMAssay Description:PROTAC activity at CRBN/LRRK2 in mouse RAW264.7 cells assessed as reduction of protein degradation measured after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed