BDBM50629518 CHEMBL5412259

SMILES Cc1nc(N2CCC3(Cc4nc(O)ccc4[C@H]3N)CC2)c2ccnn2c1-c1cccc(F)c1F

InChI Key InChIKey=YPAIQYUKPJORDA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629518   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629518(CHEMBL5412259)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length N-terminal his6-tagged human recombinant SHP2 phosphatase activity using DiFMUP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed