BDBM50629413 CHEMBL5433948

SMILES FC(F)(F)c1nnc(o1)-c1cnc(NCc2ccccc2)nc1

InChI Key InChIKey=TVEPSARMPXXYBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629413   

TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50629413(CHEMBL5433948)
Affinity DataIC50: 531nMAssay Description:Inhibition of N-terminal GST tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50629413(CHEMBL5433948)
Affinity DataIC50: 840nMAssay Description:Inhibition of N-terminal GST tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50629413(CHEMBL5433948)
Affinity DataIC50: 601nMAssay Description:Inhibition of N-terminal GST tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed