BDBM50629327 CHEMBL5428525

SMILES COc1cc(ccc1C#N)\N=C(/N)N1CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=MZIJBZJSXSVRKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629327   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629327(CHEMBL5428525)
Affinity DataIC50: 18nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629327(CHEMBL5428525)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SHP2 PTP domain (unknown origin) using DiFMUP as substrate pretreated with enzyme for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629327(CHEMBL5428525)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using DiFMUP as substrate pretreated with enzyme for 20 mins followed by substrate addition and measured for 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed