BDBM50629129 CHEMBL5440405::US20250090540, Example I-75

SMILES Cc1ccccc1Nc1ncc(cc1NC(=O)c1cc(F)cc(c1)C(F)(F)F)-c1cncc(c1)C#N

InChI Key InChIKey=ZNYHNGWAOGVTPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629129   

LigandPNGBDBM50629129(CHEMBL5440405 | US20250090540, Example I-75)
Affinity DataIC50: 100nMAssay Description:Inhibition of PIK3CA (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629129(CHEMBL5440405 | US20250090540, Example I-75)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PIK3CA (unknown origin) expressed in MCF-10A cells incubated for 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629129(CHEMBL5440405 | US20250090540, Example I-75)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent