BDBM50628993 CHEMBL5438345

SMILES O=C(CNC12CC3CC(C1)CC(C3)(C2)NCc1cccc(c1)C#N)N1Cc2ccccc2C1

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50628993   

TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50628993(CHEMBL5438345)
Affinity DataIC50: 190nMAssay Description:Inhibition of N-terminal human recombinant DPP9 expressed in Sf9 insect cells using Ala-Pro-paranitroanilide as substrate incubated for 15 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50628993(CHEMBL5438345)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal human recombinant DPP8 expressed in Sf9 insect cells using Ala-Pro-paranitroanilide as substrate incubated for 15 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50628993(CHEMBL5438345)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human seminal plasma DPP4 using Ala-Pro-paranitroanilide as substrate incubated for 15 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50628993(CHEMBL5438345)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant DPP2 using Lys-Ala-pNA as substrate incubated for 15 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGlomulin(Homo sapiens)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50628993(CHEMBL5438345)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant FAP (27 to 760 residues) expressed in Sf9 insect cells using Z-Gly-Pro-7-amino-4-methylcoumarin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50628993(CHEMBL5438345)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli BL21(DE3) using N-succinyl-Gly-Pro-AMC as substrate incubated for 15 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed