BDBM50628895 CHEMBL5415614

SMILES O[C@]1(CCN(C1)c1nc(Nc2ccnc(c2)C(F)(F)F)nc(n1)-c1cccc(n1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JYMLITLYJAHKBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628895   

TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50628895(CHEMBL5415614)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50628895(CHEMBL5415614)
Affinity DataIC50: 196nMAssay Description:Inhibition of wildtype IDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed