BDBM50628882 CHEMBL5418448

SMILES CC1=NN(C(=O)\C1=N\Nc1ccc(cc1)S(N)(=O)=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=LZLTUDYFBGBMDX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50628882   

TargetCarbonic anhydrase 12(Human)
Adiyaman University

Curated by ChEMBL
LigandPNGBDBM50628882(CHEMBL5418448)
Affinity DataKi:  6.70nMAssay Description:Inhibition of human CA XII assessed as inhibition constant by stopped-flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Adiyaman University

Curated by ChEMBL
LigandPNGBDBM50628882(CHEMBL5418448)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human CA IX assessed as inhibition constant by stopped-flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Adiyaman University

Curated by ChEMBL
LigandPNGBDBM50628882(CHEMBL5418448)
Affinity DataKi:  72nMAssay Description:Inhibition of human CA II assessed as inhibition constant by stopped-flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Adiyaman University

Curated by ChEMBL
LigandPNGBDBM50628882(CHEMBL5418448)
Affinity DataKi:  5.27E+3nMAssay Description:Inhibition of human CA I assessed as inhibition constant by stopped-flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed