BDBM50628859 CHEMBL5425250

SMILES C[C@@H]1CCCN1c1cc(nnc1N)-c1ccccc1O

InChI Key InChIKey=CMJYPZQQLQOFCI-UHFFFAOYSA-N

Data  1 IC50  4 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50628859   

TargetProtein polybromo-1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataKd:  53nMAssay Description:Binding affinity to PBRM1 bromodomain 5 (unknown origin) assessed as dissociation constant by BROMOscan LeadHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein polybromo-1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataKd:  340nMAssay Description:Binding affinity to PBRM1 bromodomain 2 (unknown origin) assessed as dissociation constant by BROMOscan LeadHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataKd:  32nMAssay Description:Binding affinity to SMARCA2 (unknown origin) assessed as dissociation constant by BROMOscan LeadHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscription activator BRG1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataKd:  33nMAssay Description:Binding affinity to SMARCA4 (unknown origin) assessed as dissociation constant by BROMOscan LeadHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataIC50: 4.30E+3nMAssay Description:Binding affinity to PXR (unknown origin) by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to LXR alpha (unknown origin) by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetOxysterols receptor LXR-beta(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to LXRbeta (unknown origin) by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataEC50: >2.00E+4nMAssay Description:Binding affinity to RXR alpha (unknown origin) by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at PPAR delta in GeneBLAzer PPARdelta-UAS-bla HEK 293T cells preincubated with compound for 16 to 24 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at PPAR gamma in GeneBLAzer PPARgamma-UAS-bla HEK 293H cells preincubated with compound for 16 to 24 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor alpha(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50628859(CHEMBL5425250)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RARalpha in GeneBLAzer RARalpha-UAS-bla HEK 293T cells preincubated with compound for 16 to 24 hrs followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed