BDBM50628681 CHEMBL5440284

SMILES COc1cn([C@@H](C[C@@H]2CCCCO2)C(=O)Nc2ccc(cc2)C(O)=O)c(=O)cc1-c1cc(Cl)ccc1C#N

InChI Key InChIKey=WVQIDDPAQZTNTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628681   

TargetCoagulation factor XI(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50628681(CHEMBL5440284)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human FXIa using Boc-Glu(OBzl)-Ala-Arg-AMC as substrate measured for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50628681(CHEMBL5440284)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human plasma Kallikrein using H-Pro-Phe-Arg-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed