BDBM50628675 CHEMBL5416199

SMILES COc1cn([C@@H](CC(C)C)C(=O)Nc2ccc(cc2)C(O)=O)c(=O)cc1-c1cc(Cl)ccc1C#N

InChI Key InChIKey=PDLAMRDOLIUATC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50628675   

TargetCoagulation factor XI(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50628675(CHEMBL5416199)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human FXIa using Boc-Glu(OBzl)-Ala-Arg-AMC as substrate measured for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed