BDBM50628302 CHEMBL5399307

SMILES OC[C@H]1CCCN1C(=O)c1ccc(OCc2noc(n2)-c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=ACESWRXKALYOHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628302   

TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50628302(CHEMBL5399307)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of SphK1 (unknown origin) using D-Sph as substrate incubated for 40 mins by ADP-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50628302(CHEMBL5399307)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of SphK2 (unknown origin) using NBD-Sph as substrate by fluorescent plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed